Withania Somnifera Extract

Active Ingredient : Alkaloids 1%, Alkaloids 2%, Withanolides 1.5% & Withanolides 2%
Common Name : Withania, Winter Cherry And Indian Ginseng
Chemical Constituents and Components : Main chemical components are glycosides, withanolides, withasomnine, hentriacontane, dulcitol, withaniol and withaferin.
Action :
Alkaloids:
1. It stimulate the generation of cytotoxic T lymphocyte thus reduces tumor growth.
2. It enhances the proliferation of lymphocytes, bone marrow cells and thymocytes.
3. It enhances the phagocytic activity of peritoneal macrophages.
4. It enhances cytokine production and stem cell proliferation and its differentiation.
Withanolides:
1. It significantly up-regulate the activity of T-helper cell.
2. It inhibits the growth of human tumor cell line.
3. It improves bone calcification and act as potential agent in the treatment of osteoporosis.
4. It increases the levels of corticosterone in the adrenal glands of stress.Curing Diseases : 1. It is used to cure anemia and rheumatoid arthritis.
2. It is useful in insomnia, tissue-building and nervous breakdown.
3. It is useful in fever, constipation and eye diseases.
4. It is used in fever, painful swellings and ulcers.Research Information : Withania somnifera extract possesses significant immunomodulatory activity. It enhances the phagocytic activity of peritoneal macrophages. (Ref. Davis, L and Kuttan, G, Immunomodulatory activity of Withania somnifera, J Ethnopharmacology, 2000 Jul; 71 (1-2): 193-200)Possible Combinations : Withania somnifera + bacopa monnerii + ginkgo biloba + ginseng + mucuna pruriens (memory enhancement)